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Ziprax® Dry Syrup

Ziprax® Dry Syrup

Ziprax® Dry Syrup is an oral antibiotic for use in pediatric patients only for the treatment of mild-to-moderate bacterial infections, including acute otitis media, sinusitis, acute bronchitis, cystitis, cystourethritis or pyelonephritis etc. Ziprax® Dry Syrup is not effective against viruses and fungi.  Show full description

Active ingredients

Other names for this medication

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Ziprax® Dry Syrup (Cefixime) 50 mg, 30 ml

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Description

Ziprax® Dry Syrup manufacturer is Cipla. Ziprax® Dry Syrup comprises an active ingredient Cefixime, a semisynthetic, oral third-generation Cephalosporin antibiotic.

Indications:

- uncomplicated urinary tract infections (e.g. cystitis, cystourethritis, uncomplicated pyelonephritis);

- upper respiratory tract infections (URTI) (e.g. otitis media, pharyngitis and tonsillitis);

- lower respiratory tract infections (LRTI) (e.g. acute exacerbations of chronic bronchitis);

- uncomplicated Gonorrhoea (cervical/urethral), which can be transmitted by infected mother to a baby during delivery.

MOA (mechanism of action):

Bactericidal action of Cefixime results in inhibition of cell-wall synthesis, which leads to the cell wall rupture and eventually bacteria’s death. Cefixime is active against gram-positive bacteria (Streptococcus pneumoniae, Streptococcus pyogenes); gram-negative bacteria (Haemophilusinfluenzae, Moraxella catarrhalis, Escherichia coli, Proteus mirabilis, Neisseria gonorrhoeae). Also, Cefixime has shown clinical efficacy in infections caused by commonly occurring pathogens, including Branhamellacatarrhalis (beta-lactamase-positive and -negative) and Enterobacter species.

Dosage

Preparation

Ziprax® Dry Syrup should be reconstituted to form an oral suspension.

1. Shake the bottle to loosen the powder.

2. Stir the dry powder with a boiled and cooled water. Recap the bottle, and shake it vigorously.

3. If necessary, add more water up to the arrow mark and shake again.

The reconstituted suspension should be consumed within 7 days after preparation. Keep it tightly closed. Shake well before each use. Throw away the unused portion after 7 days.

The recommended dose is 8 mg (0,8 ml) /kg/day of the suspension.

This may be administered as a single daily dose or may be given in two divided doses, as 4 mg (0,4 ml)/kg every 12 hours.

Children weighing more than 45 kg or older than 12 years should be treated with the recommended adult dose, 200 to 400 mg (20 to 40 ml of reconstituted suspension) daily depending on the severity of infection).

The usual duration of treatment is 7 days. This may be prolonged up to 14 days if required.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose of Ziprax® Dry Syrup to compensate the missed dose.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at a cool temperature between 15 and 20 degrees C (59 and 68 degrees F) and away from excess moisture and heat. Keep it tightly closed. Throw away any unused medicine in 5 days after reconstitution. Keep out of the reach of children.

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Side effects

The most common side effects associated with Ziprax® Dry Syrup are:

  • antibiotic-associated diarrhoea
  • abdominal pain
  • nausea
  • vomiting
  • rash
  • headache

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Ziprax® Dry Syrup if you are allergic to Cefixime or any macrolide or Cephalosporin antibiotic.

Do not use Ziprax® Dry Syrup if you are allergic to any other ingredient comprised in Ziprax® Dry Syrup.

Do not use Ziprax® Dry Syrup if you have a history of severe allergic reactions associated with using antibiotics.

Do not use Ziprax® Dry Syrup if you have severe liver or kidney problems.

Do not use Ziprax® Dry Syrup if you suffer from clostridium difficile-associated diarrhoea (CDAD).

Do not use Ziprax® Dry Syrup if you have renal impairment, are on continuous ambulatory peritoneal dialysis (CAPD) and haemodialysis (HD).

Do not use Ziprax® Dry Syrup if you have renal orhepatic impairment, or poor nutritional state.

Do not use Ziprax® Dry Syrup if you receive coumarin-type anticoagulants (e.g. Warfarin). Since Cefixime may enhance effects of the anticoagulants and cause prolonged prothrombin time with or without bleeding.

Do not use Ziprax® Dry Syrup if you have a history of drug-induced haemolytic anaemia.

Consult your doctor before taking Ziprax® Dry Syrup if you are pregnant or breastfeeding.

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Frequently asked questions

Q: What is Ziprax® Dry Syrup used for?

A: Ziprax® Dry Syrup is an oral antibiotic for use in pediatric patients only for the treatment of mild-to-moderate bacterial infections, including acute otitis media, sinusitis, acute bronchitis, cystitis, cystourethritis or pyelonephritis etc. Ziprax® Dry Syrup is not effective against viruses and fungi.

Q: Can I treat cold or flu using Ziprax® Dry Syrup?

A: Ziprax® Dry Syrup is not effective against viral infections (e.g. common cold. flu) and yeast infections.

Q: Is Ziprax® Dry Syrup safe for my child?

A: Ziprax® Dry Syrup is safe if used at prescribed doses for the prescribed treatment regime as advised by your doctor.

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  Trackable, where available5-9 business days$30.00 per order

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