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Kenadion®

Kenadion®

Kenadion® is a Vitamin K1 (Phytomenadione) in an injectable form. Phytomenadione is essential for blood clotting and in aiding the formation of bones. Kenadion® is used as an antidote to prevent bleeding if too high a dose of an anticoagulant medicine such as Warfarin has been taken.  Show full description

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Kenadion® (Vitamin K1 (Phytonadione BP)) 1 mg, 0.5 ml

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Description

Kenadion® is manufactured by Samarth. Injectable Kenadion® contains Vitamin K1 (Phytomenadione).

Vitamin K is used to treat and prevent deficiencies of certain substances (blood clotting factors). These substances help to thicken your blood and stop bleeding (e.g., after an accidental cut or injury). Low levels of blood clotting factors increase the risk for unusual bleeding. This may be caused by certain medications (Warfarin) or medical conditions (e.g., obstructive jaundice).

Thus, Kenadion® helps to treat and prevent unusual bleeding by increasing the body's production of blood clotting factors.

Dosage

Kenadion® is given by injection intravenously or intramuscularly. It may be taken with or without food.

Intravenous use

For over-anticoagulation:

RDA for adults is 0.5-5 mg via slow IV injection.

Dosage depends on INR and degree of hemorrhage.

Intramuscular use

For prophylaxis of Vitamin K deficiency bleeding in neonates:

RDA for neonates is 0.5-1 mg, given as a single dose via IM injection.

Alternatively, 2 mg may be given orally, followed by a 2nd dose of 2 mg after 4-7 days.

Parenteral use

For Vitamin K deficiency bleeding in neonates:

RDA for infants: 1 mg by IV/IM/SC injection, further doses may be given if necessary.

If this medication is given into a vein, it should be injected very slowly (no more than 1 milligram per minute) to reduce the risk of serious side effects.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not exceed the doctor's recommended dose.

Overdose

If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effects

The most common side effects associated with taking Kenadion® are:

  • irritation or inflammation of a vein
  • coughing, feeling of sickness
  • abdominal cramps
  • anaphylactic reaction
  • breathlessness
  • altered taste
  • cyanosis (bluish discoloration of the skin)
  • shortness of breath
  • flushing
  • increased bilirubin in the blood
  • decreased blood pressure
  • itching
  • skin erosion
  • skin eruptions

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Kenadion® if you are allergic to the ingredients listed in the leaflet.

Do not take anticoagulants ('blood thinners') such as Warfarin (Coumadin) while you are taking Kenadion® unless told to do so by your doctor.

If you are taking Orlistat (Xenical, Orligal, Orliford, Obelit), take it 2 hours before or 2 hours after taking Kenadion®.

Do not use Kenadion® if you need surgery or dental work, tell the surgeon or dentist ahead of time that you are using Kenadion®.

Kenadion® should be used with caution in patients with severe liver disease as the administration of high dosages may result in further depression of liver function.

Kenadion® can be harmful if you are receiving dialysis treatments due to kidney disease.

Do not use Kenadion® if you have a medical history of blood disorders.

Do not use Kenadion® if you have a medical history of gallbladder disease (e.g., obstructive jaundice, biliary fistula).

Do not use Kenadion® if you have a medical history of liver or kidney disease.

Do not use Kenadion® if you have recently used or are currently taking an antibiotic.

If you have recently used or are currently taking a blood thinner such as anisindione, heparin, warfarin, Coumadin.

If you have recently used or are currently taking Salicylates (Aspirin, Backache Relief Extra Strength, Novasal, Nuprin Backache Caplet, Doan's Pills Extra Strength, Pepto-Bismol, Tricosal etc.).

Consult your doctor before taking Kenadion® if you are pregnant, plan to have a baby or breastfeeding.

Do not consume alcohol while taking Kenadion®, as it may cause dizziness.

Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Kenadion®.

Vitamin K in some formulations contains Benzyl Alcohol, which has been reported to cause toxic and fatal reactions ("gasping syndrome") in newborn children. Discuss any questions or concerns with your doctor.

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Frequently asked questions

Q: What is Kenadion®?

A: Kenadion® is a Vitamin K1 (Phytomenadione) in an injectable form. Phytomenadione is essential for blood clotting and in aiding the formation of bones. Kenadion® is used as an antidote to prevent bleeding if too high a dose of an anticoagulant medicine such as Warfarin has been taken.

Q: How to use Kenadion®?

A: Kenadion® is given by injection intravenously or intramuscularly. It may be taken with or without food. If this medication is given into a vein, it should be injected very slowly (no more than 1 milligram per minute) to reduce the risk of serious side effects.

Q: What are possible side effects of using Kenadion®?

A: Common side effects may include irritation or inflammation of a vein, coughing, feeling of sickness, abdominal cramps, anaphylactic reaction, breathlessness.

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