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Duprost®

Duprost®

Duprost® is a medication intended for the treatment of BPH (benign prostatic hyperplasia), which mainly affects adult men. The active ingredient Dutasteride blocks the conversion of testosterone to DHT (dihydrotestosterone) – a key male hormone responsible for development and growth of the prostate gland. Duprost® has also been proven to be effective in the treatment of male pattern hair loss (MPHL).  Show full description

Active ingredients

Other names for this medication

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Duprost® (Dutasteride) 0.5mg

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Description

Duprost® is produced by Cipla. Duprost® capsules are used to treat benign prostatic hyperplasia (BPH or enlarged prostate).

Benign prostatic hyperplasia (benign prostatic hypertrophy/prostatic adenoma) is an overgrowth of cells in the central portion of the prostate. This squeezes the urethra, reduces the urine flow and makes it difficult for the patient to void his bladder.

Usual symptoms of BPH are frequent urination, urgency to urinate (compelling need to void that cannot be deferred), involuntary urination, urge incontinence, urinary hesitancy (a delay between trying to urinate and the flow actually beginning), intermittency (not continuous), involuntary interruption of voiding, weak urinary stream etc.

Each Duprost® capsule contains Dutasteride. It inhibits the action of both forms (type I and type II) of the enzyme 5α-reductase, that converts the male hormone testosterone to dihydrotestosterone (DHT).

DHT is the androgen primarily responsible for development and growth of the prostate gland. Dutasteride reduces the levels of DHT in the blood, so that prostate growth is no longer stimulated in men with BPH allowing the enlarged prostate to shrink.

This medication has also shown an improvement in men with male pattern baldness (MPB) or androgenetic alopecia but it can be used only as an off-label treatment.

DHT, which is also found in hair follicles, is the androgen responsible for hair loss, as it causes hair follicles to miniaturize and atrophy. Duprost® capsules reverse hair loss process as it blocks the build-up of DHT in the hair follicles of the scalp, allowing the hair to grow normally.

Dosage

For the treatment of BPH:

Take one capsule orally (by mouth) once a day, with or without food.

You should take the Duprost® at the same time every day.

Take Duprost® daily for at least 6 months or more if necessary before any noticeable results occur.

If Duprost® has not worked for you over a 12 months course then it is unlikely that further treatment will benefit.

Do not stop taking Duprost® suddenly, as any therapeutic benefits will be reversed.

Always consult your doctor or pharmacist if you want to stop the treatment before time or if you are intended to prolong treatment.

For the treatment of MPHL (off-label):

Take one capsule orally (by mouth) once a day, with or without food.

You should take the Duprost® capsules at the same time every day.

Take Duprost® capsules daily for at least 3 months or more if necessary before any noticeable results occur.

If Dutasteride has not worked for you over a 12 months course then it is unlikely that further treatment will benefit.

Do not stop taking Duprost® capsules suddenly, as any therapeutic benefits will be reversed.

Always consult your Duprost® or pharmacist if you want to stop the treatment before time or if you are intended to prolong treatment.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not exceed the doctor's recommended dose.

Overdose

If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effects

The most common side effects associated with Duprost® are:

  • impotence
  • decreased libido
  • decreased semen volume
  • abnormal ejaculation
  • swelling in your hands or feet
  • swelling or tenderness in your breasts
  • dizziness
  • weakness
  • feeling like you might pass out
  • headache
  • runny nose
  • skin rash

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Duprost® if you are allergic to its ingredients or allergic to a similar medication called Finasteride.

Be careful while using Duprost® if you have liver disease, undergo prostate-specific antigen assay or if you notice breast enlargement and tenderness.

Duprost® cannot be taken by women and children.

Do not donate blood until 6 months have passed since the last dose of Duprost®.

Consult a doctor before using Duprost® as it may increase your risk of developing high-grade prostate cancer.

Consult a doctor before using Duprost® if you are taking any prescription or nonprescription medications, herbal preparation, or dietary supplement.

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Frequently asked questions

Q: What is Duprost®?

A: Duprost® is a medication intended for the treatment of BPH (benign prostatic hyperplasia), which mainly affects adult men. The active ingredient Dutasteride blocks the conversion of testosterone to DHT (dihydrotestosterone) – a key male hormone responsible for development and growth of the prostate gland. Duprost® has also been proven to be effective in the treatment of male pattern hair loss (MPHL).

Q: How does Duprost® improve BPH symptoms?

A: Each Duprost® capsule contains Dutasteride. It inhibits the action of both forms (type I and type II) of the enzyme 5α-reductase, that converts the male hormone testosterone to dihydrotestosterone (DHT). DHT is the androgen primarily responsible for development and growth of the prostate gland. Dutasteride reduces the levels of DHT in the blood, so that prostate growth is no longer stimulated in men with BPH allowing the enlarged prostate to shrink.

Q: Can women take Duprost®?

A: Duprost® can never be taken by women and children.

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