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Cefoprox® Dry Syrup

Cefoprox® Dry Syrup

Cefoprox® Dry Syrup is an oral antibiotic for pediatric use in patients with upper and lower respiratory tract infections, urinary tract infections (UTIs), skin and skin structure infections. Cefoprox® Dry Syrup is not effective against viruses and fungi.  Show full description

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Cefoprox® Dry Syrup (Cefpodoxime) 50 mg, 30 ml

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Description

Cefoprox® Dry Syrup manufacturer is Cipla. Cefoprox® Dry Syrup has a tangy orange flavor. The syrup comprises an active ingredient Cefpodoxime Proxetil, an extended-spectrum and semisynthetic antibiotic of the Cephalosporin class (3rd generation).

Indications:

- upper respiratory tract infections (acute otitis media (AOM), pharyngitis and/or tonsillitis; acute bacterial sinusitis);

- lower respiratory tract infections (chronic bronchitis, community-acquired pneumonia (CAP));

- uncomplicated urinary tract infection (UTIs) like cystitis;

- uncomplicated skin and skin structure infections caused by Staphylococcus aureus (MSSA), or Streptococcus pyogenes (group A beta-hemolytic streptococci).

MOA (mechanism of action):

Cefpodoxime inhibits bacterial cell wall synthesis following binding to proteins (PBPs). This results in the rupture of cell wall (peptidoglycan) biosynthesis, which leads to bacterial cell death. Cefpodoxime has demonstrated efficacy against Moraxella catarrhalis, Haemophilus influenzae, Escherichia coli (beta-lactamase- negative strains), Klebsiella spp., Serratia spp., Proteus mirabilis, Proteus vulgaris, Providencia spp., and Salmonella spp.

Dosage

Preparation

Cefoprox® Dry Syrup should be reconstituted to form an oral suspension.

1. Shake the bottle to loosen the powder.

2. Stir the dry powder with a boiled and cooled water. Recap the bottle, and shake it vigorously.

3. If necessary, add more water up to the arrow mark and shake again.

The reconstituted suspension should be consumed within 5 days after preparation. Keep it tightly closed. Shake well before each use. Throw away the unused portion after 5 days.

For chronic bronchitis:

Children 12 years of age:

200 mg orally every 12 hours for 14 days.

For cystitis:

Adolescents and children over 12 years:

100 mg orally every 12 hours for 7 days.

Shorter therapy duration (2 to 4 days) may be used in older children with uncomplicated cystitis.

For acute otitis media (AOM):

Children 6 years and older:

5 mg/kg/dose orally every 12 hours (max: 200 mg/dose) for 5 days.

Children between 2 months and 5 years:

5 mg/kg/dose orally every 12 hours for 5 days.

For uncomplicated skin and skin structure infections:

Adults, adolescents, and children over 12 years:

400 mg orally every 12 hours for 7 to 14 days.

For pharyngitis and/or tonsillitis:

Adolescents:

100 mg orally every 12 hours for 5 to 10 days.

Infants 2 months and older:

5 mg/kg orally every 12 hours for 5 to 10 days (max: 100 mg/dose).

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not use a double dose of Cefoprox® Dry Syrup to compensate the missed dose.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at a cool temperature between 15 and 20 degrees C (59 and 68 degrees F) and away from excess moisture and heat. Keep it tightly closed. Throw away any unused medicine in 5 days after reconstitution. Keep out of the reach of children.

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Side effects

The most common side effects associated with Cefoprox® Dry Syrup are:

  • antibiotic-associated diarrhoea
  • abdominal pain
  • nausea
  • vomiting
  • rash
  • headache

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Cefoprox® Dry Syrup if you are allergic to Cefpodoxime or to any other cephalosporins.

Do not use Cefoprox® Dry Syrup if you are allergic to any other ingredient comprised in Cefoprox® DT.

Do not use Cefoprox® Dry Syrup if you have a history of severe allergic reactions associated with using antibiotics.

Do not use Cefoprox® Dry Syrup if you suffer from pseudo-membranous colitis.

Do not use Cefoprox® Dry Syrup if you have severe liver or kidney problems.

Do not use Cefoprox® Dry Syrup if you are taking Aminoglycosides (e.g., Gentamicin), cyclosporine, or diuretics (e.g., Furosemide, Hydrochlorothiazide).

Cefoprox® Dry Syrup should not be given within 2 hours of antacids or H2 antagonists (e.g., Famotidine).

Patients with diabetes mellitus who test their urine for glucose should use glucose tests based on enzymatic glucose oxidase reactions while using Cefoprox® DT.

Consult your doctor before using Cefoprox® Dry Syrup if you are pregnant or breastfeeding.

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Frequently asked questions

Q: What is Cefoprox® Dry Syrup used for?

A: Cefoprox® Dry Syrup is an oral antibiotic for pediatric use in patients with upper and lower respiratory tract infections, urinary tract infections (UTIs), skin and skin structure infections.

Q: Can I treat cold or flu using Cefoprox® Dry Syrup?

A: Cefoprox® Dry Syrup is not effective against viruses and fungi.

Q: Is Cefoprox® Dry Syrup safe for my child?

A: Cefoprox® Dry Syrup is safe if used at prescribed doses for the prescribed treatment regime as advised by your doctor.

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