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Ampicillin®

Ampicillin®

Ampicillin® is an oral antibiotic used to kill bacteria that cause infections in your body such as pneumonia, bronchitis, Enteric (Typhoid) fever, Septicaemia, Gonorrhoea, peritonitis, meningitis and other dangerous diseases. Ampicillin® cannot be used to treat viral infections like flu or cold.  Show full description

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Description

Ampicillin® is produced by Omega. Ampicillin® capsules comprise Ampicillin as raw material. It is an extended-spectrum third generation Aminopenicillin (drug class Penicillins), a beta-lactam sensitive antibiotic with antimicrobial activity against Listeria monocytogenes, Escherichia coli, Salmonella typhi, Haemophilus influenzae, Streptococcus pneumonia, Streptococcus pyrogenes, Neisseria meningitidis, Proteus mirabilis, and Enterococcus faecalis.

Indications:

- respiratory tract infections (e.g. infections of the nose and throat, pneumonia, bronchitis);

- infections of the ear;

- urinary tract infections (e.g. infections of the bladder and urethra);

- gastrointestinal infections (e.g. infections of the intestines);

- Enteric/Typhoid fever (an infectious disease contracted by eating food or drinking water contaminated with Salmonella);

- gynecological infections and STDs (sexually transmitted disease like Gonorrhoea);

- infections of the blood (Septicaemia);

- skin and soft tissue infections (e.g. acne);

- prevention of endocarditis (inflammation of the lining of the heart and its valves) after surgery or a dental procedure;

- peritonitis (an inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen);

- meningitis (inflammation of the protective membranes covering the brain and spinal cord) is usually treated by Ampicillin intravenously or intramuscularly.

MOA (mechanism of action):

Ampicillin a bactericidal drug, that interferes with the last step of bacterial cell wall synthesis, resulting in exposure of membrane and further cell damaging. Ampicillin is only effective against fast growing microorganisms that synthesize a peptidoglycan cell wall. Therefore, Ampicillin is inactive against organisms devoid of this structure, such as mycobacteria, protozoa, fungi, and viruses.

Dosage

Ampicillin® capsules should be taken orally on an empty stomach, at least 30 minutes to one hour before meals.

Adults and elderly

For infections of ear, nose and throat, bronchitis: 250 mg four times daily.

This may be increased to 1gram four times daily in certain cases.

For pneumonia: 500 mg four times daily.

For urinary tract infections: 500 mg three times daily.

For gastrointestinal infections: 500-750 mg three to four times daily.

For typhoid fevers:

Acute: 1-2 g four times daily for 2 weeks.

Carriers: 1-2 g four times daily for 4 to 12 weeks.

For Gonorrhoea: 2 g orally with 1 g of probenecid as a single dose. A repeated dose may be required in women.

The dosage may be reduced in patients with severe kidney failure.

Children under 10 years (20 kg or less)

For genitourinary or gastrointestinal tract infections: 100 mg/kg/day total, 4 times daily in equally divided and spaced doses.

For respiratory infections: 50 mg/kg/day total, in equally divided and spaced doses 3 to 4 times daily.

Duration of treatment of all infections should be continued for a minimum of 48 to 72 hours after the patient becomes asymptomatic or evidence of bacterial eradication has been obtained.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose of Ampicillin® to compensate the missed dose.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effects

The most common side effects associated with Ampicillin® are:

  • antibiotic-associated diarrhea
  • allergic reactions
  • nausea
  • vomiting
  • swelling of the lips, cheeks, tongue and eyelids
  • skin rash, itching
  • yellowing of the whites of the eyes and skin
  • discomfort in passing urine
  • blood in the urine
  • lower back pain

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Ampicillin® if you are allergic to Ampicillin or to other Penicillins.

Do not take Ampicillin® if you are allergic to any ingredient comprised in Ampicillin®.

Do not take Ampicillin® if you have a history of severe allergic reactions associated with using antibiotics.

Do not take Ampicillin® if you have kidney problems.

Do not take Ampicillin® if you have you have mononucleosis.

Do not take Ampicillin® if you have if you have a stomach infection or diarrhea.

Do not take Ampicillin® if you have if you have a history of clostridium difficile associated diarrhea (CDAD).

Do not take Ampicillin® if you suffer from glandular fever or cytomegalovirus (CMV) infection.

Do not take Ampicillin® if you suffer from lymphatic leukemia.

Do not take Ampicillin® if you take other medications, including Allopurinol, sulfinpyrazone or probenecid (for gout); Tetracycline, Erythromycin (Erythro®) and chloramphenicol (other antibiotics); anticoagulants (e.g. Warfarin) or phenindione; cytotoxic drugs e.g. Methotrexate (for rheumatoid arthritis, psoriasis, or lymphatic leukaemia); Chloroquine (for prevention and treatment of malaria); oral typhoid vaccine (for preventing typhoid).

Do not take Ampicillin® if you are pregnant, plan to have a baby or are breastfeeding.

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Frequently asked questions

Q: What is Ampicillin® used for?

A: Advent® Drops is a bactericidal beta-lactam antibiotic with a tangy orange flavor aimed to kill bacterial infections including urinary tract infections, respiratory tract infections, skin and soft tissue infections like wound infections and infected animal bites, dental infections in infants weighing between 4-10 kg.

Q: Is Ampicillin® safe?

A: Ampicillin® is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Q: Can I take Ampicillin® for a cold?

A: Ampicillin® cannot be used to treat viral infections like flu or cold.

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